Welcome to the IdeaBounce® website for the Skandalaris Center for Interdisciplinary Innovation & Entrepreneurship at Washington University in St. Louis. Since 2005, the IdeaBounce® site and events have helped early-stage entrepreneurs connect with each other and with the resources they need to help move their ideas forward. In addition to this site for all ideas, we also host sites specific to the 2014 Olin Cup and the 2015 YouthBridge Social Enterprise and Innovation Competition. Please note the welcome kit has not yet been updated for the 2015 YouthBridge Social Enterprise and Innovation competition, but you may click the links above to view the welcome kits from last year.
We also make the IdeaBounce® website available to universities and community partners who wish to administer their own sites and host their own events. Visit the following sites to see how others are using the IdeaBounce® concept and contact us at email@example.com if you'd like your own!
HER (ErbB) receptors are associated with multiple cancers. Treatments target the extracellular domain with mABs or the intracellular tyrosine kinase domain with small-molecule inhibitors (RTKIs). Either approach is usually short lived and leads to recurrence and metastasis. A third approach prevents both hetero- and homodimerization of HER receptors, essential for activation of intracellular signaling, and is not affected by resistance to either mABs or RTKIs. Thus, recurrent cancers riven by HER receptors can be treated HER-dimerization inhibitors we have developed.
We have successfully established a biomarker assay for cancer detection and diagnosis in a small trial. This biomarker assay detected 80 -100% of ovarian, lung and pancreatic cancers with no false positives. We apply the Bear Cub fund to validate the biomarker assay by increasing body biofluid sample numbers. The immediate goal of the proposed study is to develop a sensitive, specific, noninvasive, economical, and easily performed assay for cancer detection and diagnosis.
Plant and Life Science,
Adenovirus-based vaccines applied to cancer and infectious diseases have recently demonstrated efficacy in human clinical trials. We have developed a novel technology which dramatically augments the potency of adenovirus vaccines by targeting them to the key immunoregulatory dendritic cells. This competitive advantage provides the basis for diverse joint development based upon the potency enhancements our targeting technology accrues. Bear Cub funding will allow us to accomplish key proof-of-principle studies that will define products for full translational/commercial development.
Plant and Life Science
Operations and Management
Too many young talented students are not engaged by their classes or homework. Very bright students are not enjoying school. We seek to reignite the passion to learn and discover that all children are born with. Discovery Ninja is a platform for online classes that are fun and hands-on. We are aiming for middle school and early high school students but are helpful for any age. Our courses will be aimed at helping students develop real skills and cross-discipline understanding of concepts. Students begin and complete a fun projects so they are able to see real results of their efforts.
We live in a modern era of accessible technology, convenience, instant gratification, and shortened attention spans. The charity platform, mindset, and volunteer experience has failed to adapt to our modern philanthropic needs. The Deeds App is a mobile application that focuses on accomplishing geotagged good deeds, rewarding volunteers, and supporting locally owned businesses. The Deeds App combines the core elements of crowdfunding, freelancing, charity, daily deals, and social media to create a full circle approach to community development and economic growth.
Finance and Accounting